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Longevity

MOTS-c

Mitochondria-derived peptide. Metabolic and exercise mimetic.
MS10

MOTS-c is produced inside mitochondria and acts as a signaling molecule throughout the body. It activates AMPK, the same pathway targeted by metformin, improving insulin sensitivity and promoting fat oxidation. Animal studies show exercise-mimetic effects, making it compelling for metabolic support and longevity.

Insulin SensitivityFat OxidationAMPK ActivationExercise MimeticMitochondrial HealthMetabolic Support
MOTS-c naturally increases in response to exercise and caloric restriction. Injectable MOTS-c essentially mimics that signal pharmacologically. It is an emerging compound with strong mechanistic rationale and growing community use. Particularly interesting for members who want metabolic support without the GI burden of GLP-1 peptides, or as an addition to a GLP-1 protocol for broader metabolic coverage. Pairs especially well with NAD+ for a comprehensive mitochondrial support stack.
Mixing Instructions
1
Add 2mL bacteriostatic water to your 10mg vial.
2
Swirl gently until clear. Label with date.
3
Refrigerate. For best results, use within 28 days of reconstitution.

Based on standard reconstitution above. All doses subcutaneous unless noted.

DoseSyringe (units)Volume (mL)
2.5mg50 units0.5mL
5mg100 units - one full syringe1mL
10mg2 syringes2mL
Research Protocol
Dose5-10mg, 2-3 times per week
Common5mg every other day
RouteSubcutaneous or IM
Cycle8-12 week cycles
TimingPre-workout or morning for metabolic support
All BodhiPep compounds are for research use only. For educational purposes only.