What it does
Weight LossMetabolic HealthVisceral FatInsulin SensitivityEnergy Expenditure
Retatrutide targets GLP-1, GIP, and glucagon receptors simultaneously. The GLP-1 component slows gastric emptying and suppresses appetite. GIP enhances the insulin response. Glucagon receptor activity boosts energy expenditure and fat oxidation, making Retatrutide meaningfully more powerful than single or dual agonists. Titrate slowly. GI side effects front-load during escalation and improve significantly by week 4-6. Adequate protein intake is critical during rapid weight loss to preserve lean mass.
Reconstitution
Mixing Instructions
1
Add 2mL bacteriostatic water to your vial (RT10 & RT20). RT15 → use 3mL.
2
Inject slowly down the glass wall. Do not aim at the powder.
3
Gently swirl until fully clear. Do not shake.
4
Label with date. Refrigerate immediately. For best results, use within 28 days of reconstitution.
Dosing Reference
Based on standard reconstitution above. All doses subcutaneous unless noted.
All vial sizes reconstitute to 5mg/mL: RT10 → 2mL · RT15 → 3mL · RT20 → 2mL. Once weekly subcutaneous.
| Dose | Syringe (units) | Volume (mL) |
|---|---|---|
| 0.50mg — common start | 10 units | 0.10mL |
| 1.00mg | 20 units | 0.20mL |
| 1.50mg | 30 units | 0.30mL |
| 2.00mg | 40 units | 0.40mL |
| 2.50mg | 50 units | 0.50mL |
Protocol
Research Protocol
Weeks 1-42mg per week (1mg x2, Mon/Thu)
Weeks 5-84mg per week (2mg x2, Mon/Thu)
Weeks 9-126mg per week (3mg x2, Mon/Thu)
Weeks 13+8-12mg per week based on tolerance
RouteSubcutaneous - abdomen, thigh, or upper arm
Cycle12-48 weeks
Split doseRecommended - divide weekly dose Mon/Thu
All BodhiPep compounds are for research use only. For educational purposes only.